Standard Practice for Validation of Empirically Derived Multivariate Calibrations

Importancia y uso:

5.1 This practice outlines a universally applicable procedure to validate the performance of a quantitative or qualitative, empirically derived, multivariate calibration relative to an accepted reference method.

5.2 This practice provides procedures for evaluating the capability of a calibration to provide reliable estimations relative to an accepted reference method.

5.3 This practice provides purchasers of a measurement system that incorporates an empirically derived multivariate calibration with options for specifying validation requirements to ensure that the system is capable of providing estimations with an appropriate degree of agreement with an accepted reference method.

5.4 This practice provides the user of a measurement system that incorporates an empirically derived multivariate calibration with procedures capable of providing information that may be useful for ongoing quality assurance of the performance of the measurement system.

5.5 Validation information obtained in the application of this practice is applicable only to the material type and property range of the materials used to perform the validation and only for the individual measurement system on which the practice is completely applied. It is the user's responsibility to select the property levels and the compositional characteristics of the validation samples such that they are suitable to the application. This practice allows the user to write a comprehensive validation statement for the analyzer system including specific limits for the validated range of application and specific restrictions to the permitted uses of the measurement system. Users are cautioned against extrapolation of validation results beyond the material type(s) and property range(s) used to obtain these results.

5.6 Users are cautioned that a validated empirically derived multivariate calibration is applicable only to samples that fall within the subset population represented in the validation set. The estimation from an empirically derived multivariate calibration can only be validated when the applicability of the calibration is explicitly established for the particular measurement for which the estimation is produced. Applicability cannot be assumed.

Subcomité:

E13.11

Referida por:

D7825-24, D8431-22, D7889-21, C1307-21, E2475-23, E2898-20A, E2891-20

Volúmen:

03.06

Número ICS:

17.020 (Metrology and measurement in general)

Palabras clave:

calibrations; empirically derived multivariate calibrations; validation;