Standard Practice for Recovery of Microorganisms From Skin using the Cup Scrub Technique

Importancia y uso:

5.1 The procedure can be incorporated into protocols used to evaluate test materials containing antibacterial ingredients that are intended to reduce significantly the number of organisms on intact skin. It also may be used to provide an indication of residual antibacterial activity (as in Guide E2752). Examples of test materials, for which this practice is applicable, include pre-operative skin preparations, hand-washes, surgical scrubs, acne reduction products, and others. For each type of test material, types of resident flora or surrogate organisms, or a combination thereof, may differ and should be considered (this is, aerobic bacteria, anaerobic bacteria, yeast, or mold).

5.2 The procedure may be used in protocols intended to evaluate and identify resident flora from the skin.

5.3 Performance of this technique may require the knowledge of regulations pertaining to the protection of human subjects if the protocol involves application of the technique to the skin of human subjects.

Subcomité:

E35.15

Referida por:

E1173-23, E2897-22, E1589-21

Volúmen:

11.08

Número ICS:

71.100.40 (Surface active agents)

Palabras clave:

cup scrub; resident flora; skin; skin equivalent; transient organism;