Standard Practice for Detailed Clinical Observations of Test Animals

Importancia y uso:

3.1 This practice pertains to all forms of toxicological testing (acute, subchronic, or chronic) performed by any route of administration (inhalation, oral, dermal, ocular, or other).

3.2 The U.S. Environmental Protection Agency, Good Laboratory Practices for Nonclinical Laboratory Studies, as listed in 40 CFR, requires that a testing facility maintain specific standard operating procedures (SOPs) including an SOP covering clinical observations in test animals.

3.3 This practice serves as a basis for consistency in clinical observations and is not meant to serve as a comprehensive list of observations that may be observed. Actual procedures and forms to be used in recording observations must be described in individual study protocols.

Subcomité:

E50.47

Volúmen:

11.09

Número ICS:

11.220 (Veterinary medicine)

Palabras clave:

adverse reactions; animals; clinical codes; clinical signs; toxicity;