Standard Test Method for Determination of 2,4-Toluene Diisocyanate (2,4-TDI) and 2,6-Toluene Diisocyanate (2,6-TDI) in Workplace Atmospheres (1-2 PP Method)

Importancia y uso:

5.1 Diisocyanates are used in the production of polyurethane foams, plastics, elastomers, surface coatings, and adhesives (5, 6). It has been estimated that the production of TDI will steadily increase during the future years.

5.2 Diisocyanates are irritants to eyes, skin, and mucous membrane and are respiratory sensitizers. Chronic exposure to low concentrations of diisocyanates produces an allergic sensitization which may progress into asthmatic bronchitis (7, 8).

5.3 The United States Occupational Safety and Health Administration (OSHA) has a permissible exposure limit (PEL) for 2,4-TDI of 0.02 ppm or 0.14 mg/m³ as a ceiling limit. There is no OSHA PEL for 2,6-TDI (9). The American Conference of Governmental Industrial Hygienists (ACGIH) has a time–weighted average (TWA) Threshold Limit Value (TLV) of 0.001 ppm or 0.007 mg/m³ and a short-term exposure limit (STEL) of 0.005 ppm or 0.036 mg/m³ for either 2,4-TDI, or 2,6-TDI, or for a mixture of 2,4- and 2,6-TDI (10).

Subcomité:

D22.04

Volúmen:

11.07

Número ICS:

13.040.30 (Workplace atmospheres)

Palabras clave:

2,4-toluene diisocyanate; 2,6-toluene diisocyanate;1-(2-pyridyl)piperazine; 2,4-TDI; 2,6-TDI; air monitoring; high-performance liquid chromatography; sampling and analysis; workplace atmospheres;